Some prescription drugs have a very narrow therapeutic window, meaning the exact dosage is really important.
一些处方药治疗窗口非常狭窄，这意味着准确的剂量非常重要。
| 单词 | Therapeutic window |
| 释义 |
Therapeutic window
原声例句
Scishow 精选系列 Some prescription drugs have a very narrow therapeutic window, meaning the exact dosage is really important. 一些处方药治疗窗口非常狭窄，这意味着准确的剂量非常重要。 2017级专外有声 Indapamide has a larger therapeutic window for hypertension (without pronounced diuresis) than most other diuretics. 与其他大多数的利尿剂相比，吲达帕胺对高血压(无明显利尿)有更大的治疗窗口。
英语百科
Therapeutic index（重定向自Therapeutic window）
The therapeutic index (TI) (also referred to as therapeutic window or safety window or sometimes as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity. Classically, in an established clinical indication setting of an approved drug, TI refers to the ratio of the dose of drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD50) divided by the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of subjects, ED50). In contrast, in a drug development setting TI is calculated based on plasma exposure levels. |
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