A ventricular septal defect is when this lower wall—the ventricular septum— has a gap in it after development.

室间隔缺损就是位于心脏下方的室间隔，在发育之后存在一个缺口。

If these don't fuse though, then a gap is left between the two chambers, in other words, a ventricular septal defect, or VSD.

如果这些组织不能融合起来，就会在两个心腔之间留有一个缺口，也就是室间隔缺损，简称VSD。

Other conditions that cause audible systolic murmurs include ventricular septal defect and mitral valve prolapse.

产生可闻及的收缩期杂音的其他情况包括室间隔缺损和二尖瓣脱垂。

If you have a ventricular septal defect, again, your heart is going to have to start working a lot harder.

如果室间隔缺损，同样，心脏将不得不开始更加努力地工作。

Some possibilities are having the foramen ovale or ductus arteriosus stay open, or for the baby to have what's called a ventricular septal defect, where there's a shunt between the ventricles —which is actually present in about a third of cases.

也有可能的是卵圆孔和动脉导管仍然开放，或者一些婴儿有所谓的室间隔缺损，即在室间隔之间有分流，这在大概三分之一的病例中是存在的。