Prothrombin complex concentrate
(重定向自Prothrombin complex)
Prothrombin complex concentrate (PCC, trade names Beriplex, Octaplex, Kcentra, Cofact, among others) is a combination of blood clotting factors II, VII, IX and X, as well as protein C and S, prepared from fresh-frozen human blood plasma. It is used to reverse the effects of oral anticoagulation therapy when bleeding occurs (e.g. in the brain or gut) requiring rapid action to accelerate coagulation.