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单词 Apoptosome
释义

Apoptosome

英语百科

Apoptosome

3D structure of the human apoptosome-CARD complex. blue=apoptosome platform; magenta= CARD disk (Yuan et al. 2010, Structure of an apoptosome-procaspase-9 CARD complex[1])
Pseudo atomic structure of the human apoptosome (Yuan et al. 2010, Structure of an apoptosome-procaspase-9 CARD complex [1]
Human, fruit fly, & nematode apoptosomes

The apoptosome is a large quaternary protein structure formed in the process of apoptosis. Its formation is triggered by the release of cytochrome c from the mitochondria in response to an internal (intrinsic) or external (extrinsic) cell death stimulus. Stimuli can vary from DNA damage and viral infection to developmental cues such as those leading to the degradation of a tadpole's tail.

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更新时间:2025/6/20 13:36:36