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单词 DNA primase
释义

DNA primase

中文百科

引发酶 Primase

(重定向自DNA primase)

引发酶英语:primase)是指在DNA复制的起始阶段合成单链RNA引物的RNA聚合酶,引物合成后,DNA聚合酶会沿着引物继续合成单链DNA(延伸),此后RNA引物片段会被外切酶5'到3'方向切除。

引发酶催化一个称为引物的短RNA(或某些生物的DNA)片段的合成,并与单链DNA模板互补。引发酶是DNA复制起始阶段的关键酶之一,因为没有任何已知DNA聚合酶能在没有起始引物的情况下合成DNA。

英语百科

Primase 引发酶

(重定向自DNA primase)
Figure 1. Select multifunctional primases across three domains of life (eukaryota, archaea, and bacteria). The ability of a primase to perform a particular activity is indicated by a check mark. Adapted from [6].

DNA primase, also called as DNA primerase, is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA (or DNA in some organisms ) segment called a primer complementary to a ssDNA template. Primase is of key importance in DNA replication because no known DNA polymerases can initiate the synthesis of a DNA strand without an initial RNA or DNA primer (for temporary DNA elongation). After this elongation the RNA piece is removed by a 5' to 3' exonuclease and refilled with DNA.

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更新时间:2025/6/21 23:34:18