These causes of sideroblastic anemia stops the iron from being incorporated to form heme, which allows the iron to accumulate in the mitochondria, resulting in Pappenheimer bodies seen on blood film.
这些导致铁粒幼细胞性贫血的原因阻止了铁结合形成血红素的过程,使得铁在线粒体内积累,从而导致在血涂片上可见帕彭海默氏小体。