Procollagen-proline dioxygenase

（重定向自Prolyl hydroxylase）

A closer view of the substrate binding domain of prolyl hydroxylase. Tyrosine residues, which form the binding groove, are displayed in yellow.

Procollagen-proline dioxygenase, commonly known as prolyl hydroxylase, is a member of the class of enzymes known as 2-oxoglutarate-dependent dioxygenases. These enzymes catalyze the incorporation of oxygen into organic substrates through a mechanism that requires 2-oxoglutarate, Fe, and ascorbate. This particular enzyme catalyzes the formation of (2S, 4R)-4-hydroxyproline, a compound that represents the most prevalent post-translational modification in the human proteome.

单词	Prolyl hydroxylase
释义	Prolyl hydroxylase 英语百科 Procollagen-proline dioxygenase （重定向自Prolyl hydroxylase） Procollagen-proline dioxygenase, commonly known as prolyl hydroxylase, is a member of the class of enzymes known as 2-oxoglutarate-dependent dioxygenases. These enzymes catalyze the incorporation of oxygen into organic substrates through a mechanism that requires 2-oxoglutarate, Fe, and ascorbate. This particular enzyme catalyzes the formation of (2S, 4R)-4-hydroxyproline, a compound that represents the most prevalent post-translational modification in the human proteome.
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