OTOF

Otoferlin is a protein that in humans is encoded by the OTOF gene.

Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multiple isoforms have been found for this gene.

单词	Otoferlin
释义	Otoferlin 英语百科 OTOF Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multiple isoforms have been found for this gene.
随便看	methylglyoxime的意思 methyl glyoxime的意思 methylglyoxyl bis guanylhydrazone的意思 methylgreen的意思 methyl green的意思 methyl green pyronin的意思 methyl green pyronine的意思 methyl green pyronine stain的意思 methyl green pyronine staining的意思 methylgreen pyronin ribonuclease method的意思 methyl green pyronin stain的意思 methylgreen pyronin stain的意思 methyl green pyronin staining的意思 methylgrignardreagent的意思 methyl grignard reagent的意思 methyl group的意思 methyl group的意思 methylguaiacol的意思 Methylguanidinase的意思 methylguanidine的意思 methyl guanidine的意思 methyl guanidine acetic acid的意思 Methyl guanidine hydrochloride的意思 methylguanidine nitrate的意思 methylguanidine sulfate的意思