Molecular recognition

Crystal structure of a short peptide L-Lys-D-Ala-D-Ala (bacterial cell wall precursor) bound to the antibiotic vancomycin through hydrogen bonds[1]

Crystal structure of two isophthalic acids bound to a host molecule through hydrogen bonds[2]

Static recognition between a single guest and a single host binding site. In dynamic recognition binding the first guest at the first binding site induces a conformation change that affects the association constant of the second guest at the second binding site. In this case it is positive allosteric system.

The term molecular recognition refers to the specific interaction between two or more molecules through noncovalent bonding such as hydrogen bonding, metal coordination, hydrophobic forces, van der Waals forces, π-π interactions, halogen bonding, electrostatic and/or electromagnetic effects. In addition to these direct interactions as well solvent can play a dominant indirect role in driving molecular recognition in solution. The host and guest involved in molecular recognition exhibit molecular complementarity.

单词	Molecular recognition
释义	Molecular recognition 英语例句库 Molecular recognition by use of metalloporphyrin as host molecules are reviewed. 综述了金属卟啉配合物的分子识别研究进展。 Molecular recognition of size and shape, functional group, as well as chirality of guests by metalloporphyrin hosts are discussed in detail. 介绍了金属卟啉配合物在分子形状与大小识别、官能团识别和手性识别方面的研究概况。英语百科 Molecular recognition The term molecular recognition refers to the specific interaction between two or more molecules through noncovalent bonding such as hydrogen bonding, metal coordination, hydrophobic forces, van der Waals forces, π-π interactions, halogen bonding, electrostatic and/or electromagnetic effects. In addition to these direct interactions as well solvent can play a dominant indirect role in driving molecular recognition in solution. The host and guest involved in molecular recognition exhibit molecular complementarity.
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