Exogenous DNA

Exogenous DNA refers to any deoxyribonucleic acid that originates outside of the organism of concern or study.

The introduction of exogenous DNA into a cell is called transformation (transfection in animal cells). This can take place naturally or artificially. Methods of artificial transfection include (a) chemical methods, including calcium phosphate precipitation, DEAE-dextran complexation and lipid-mediated DNA transfer; (b) physical methods, including electroporation, microinjection, and biolistic particle delivery (gene gun); and (c) using recombinant, lab manipulated viruses as vectors.