Differential extraction

Workflow of the differential lysis of a sample of sexual assault evidence is shown. All steps of the stepwise DNA-extraction process are described in detail.

Differential extraction (also known as differential lysis) refers to the process by which the DNA from two different types of cells can be extracted without mixing their contents. The most common application of this method is the extraction of DNA from vaginal epithelial cells and sperm cells from sexual assault cases in order to determine the DNA profiles of the victim and the perpetrator. Its success is based on the fact that sperm cells have protein disulfide bonds in their outer membrane which makes them more resilient to extraction than epithelial cells.

单词	Differential extraction
释义	Differential extraction 英语百科 Differential extraction Differential extraction (also known as differential lysis) refers to the process by which the DNA from two different types of cells can be extracted without mixing their contents. The most common application of this method is the extraction of DNA from vaginal epithelial cells and sperm cells from sexual assault cases in order to determine the DNA profiles of the victim and the perpetrator. Its success is based on the fact that sperm cells have protein disulfide bonds in their outer membrane which makes them more resilient to extraction than epithelial cells.
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