Microscopic examination can show tumor cells with a characteristic abnormal elongated shape, called spindle cells.

镜检可看到典型的异常细长形状的肿瘤细胞，叫做梭形细胞。

So, it means that your gene, your DNA can mutate, and that could make, for example, the shape of the organism change to abnormal shapes.

所以，这意味着你的基因，你的脱氧核糖核酸可以变异，这可能会使生物的形状变得异常。

But in Alzheimer's disease, Tau is modified, causing it to dissociate from the microtubules, adopt an abnormal shape and move from the axon to the cell body.

但在阿尔茨海默氏症中，Tau 被修饰，导致它从微管中分离出来，采用异常形状并从轴突移动到细胞体。