凯丽·安东尼之死是指2008年美国佛罗里达州的一名两岁女童凯丽·玛丽·安东尼（Caylee Marie Anthony）失踪，数月后警方在树林中发现用塑料袋包裹的凯丽·安东尼的遗体的案件。

凯丽的母亲凯西·安东尼（Casey Anthony）被控杀害自己的亲生女儿凯丽。该案件发生后受到媒体广泛关注，凯西对警方作假证，以及她在女儿失踪后的反常举动都成为对她不利的因素。然而在近四年的审理过程中，没有足够证据给她定罪。凯西宣称女儿是在游泳时意外溺死，由于害怕凯丽的父亲乔治，所以才选择藏尸隐藏真相。她最终于2011年7月13日被释放。

Caylee Marie Anthony (August 9, 2005 – 2008) was a two-year-old American girl who lived in Orlando, Florida, with her mother, Casey Marie Anthony, and her maternal grandparents, George and Cindy Anthony. On July 15, 2008, she was reported missing in a 9-1-1 call made by Cindy, who said she had not seen Caylee for 31 days and that Casey's car smelled like a dead body had been inside it. Cindy said Casey had given varied explanations as to Caylee's whereabouts before finally telling her that she had not seen Caylee for weeks. Casey told detectives several falsehoods, including that the child had been kidnapped by a nanny on June 9, and that she had been trying to find her, too frightened to alert the authorities. She was charged with first-degree murder in October 2008 and pleaded not guilty.