卡比博-小林-益川矩阵（Cabibbo-Kobayashi-Maskawa，CKM或KM matrix）是粒子物理标准模型的一个重要组成成份，它表征了顶类型和底类型夸克间通过W粒子弱相互作用的耦合强度。对二代夸克情形，它是由意大利物理学家卡比博在1963年首先给出的，通常被称为卡比博矩阵或卡比博角。1973年日本物理学家小林诚和益川敏英把它推广到三代夸克。三代矩阵含有相位，可以用来解释弱相互作用中的电荷宇称对称性破缺（CP破坏），也被经常用来解释宇宙重子数不对称。CKM矩阵在轻子中的对应是牧-中川-坂田矩阵（Maki-Nakagawa-Sakata或MNS）。

In the Standard Model of particle physics, the Cabibbo–Kobayashi–Maskawa matrix (CKM matrix, quark mixing matrix, sometimes also called KM matrix) is a unitary matrix which contains information on the strength of flavour-changing weak decays. Technically, it specifies the mismatch of quantum states of quarks when they propagate freely and when they take part in the weak interactions. It is important in the understanding of CP violation. This matrix was introduced for three generations of quarks by Makoto Kobayashi and Toshihide Maskawa, adding one generation to the matrix previously introduced by Nicola Cabibbo. This matrix is also an extension of the GIM mechanism, which only includes two of the three current families of quarks.