It restricts blood flow to lower limbs, resulting in brittle bones.

这种病会限制血液流动到下肢，导致脆骨症。

Gaelynn was born with brittle bone disease, which has left her in a wheelchair.

Gaelynn 患有先天性脆性骨折病，因此她需要借助轮椅生活。

Plus, my conditioner decided to stop working and I think I have brittle bones.

所以我决定停止工作，我身心俱疲。

The negative ones cover a wide variety, from brittle bones to cancer, and cardiovascular diseases to intolerance and allergies.

负面因素涵盖多种多样，从脆弱的骨骼到癌症，再到心血管疾病再到不宽容和过敏。

In fact, doctors recommend that women with brittle bones avoid a natural birth altogether, which could mean births in space would be left to other methods.

事实上，医生推荐骨质疏松的女人尽量避免自然分娩，这也就意味着太空分娩将采用其他方式。

Resulting from the increased breakdown of most types of tissue, the individual presents with muscle wasting and thin extremities, skin thinning, easy bruising and abdominal striae or lines as well as fractures due to osteoporosis or brittle bones.

大多数组织分解导致患者出现肌肉萎缩和四肢瘦弱、皮肤变薄、易出现瘀伤和腹部出现皮纹，以及由骨质疏松或骨骼脆弱引起的骨折。

The findings will fuel interest in radical new therapies that aim to slow or reverse the aging process as a means of tackling age-related diseases such as cancer, brittle bones and Alzheimer's.

这一发现会点燃人们对以延缓或逆转衰老为目标的激进新疗法的兴趣，这种疗法可以用来治疗癌症、骨质疏松和老年痴呆症等老年常见疾病。