The capsid is covered by a protein layer called the tegument, and finally enclosed in an envelope, which is a lipid membrane that contains viral glycoproteins and is acquired from the nuclear membrane of host cells.

衣壳上覆盖有一层叫“间层”的蛋白，最外面由一层囊膜包裹；囊膜是一层包含病毒糖蛋白的磷脂膜，来自于宿主细胞的核膜。

HHV-8 is transmitted through sexual contact, and once in the body, it uses the viral glycoproteins on its envelope to enter a wide variety of cells, such as B cells, endothelial cells, macrophages and epithelial cells.

HHV-8通过性接触传播，一旦进入宿主体内，它会利用囊膜上的病毒糖蛋白进入多种细胞内，例如B细胞、内皮细胞、巨噬细胞与上皮细胞。