南达科他大学是美国南达科他州的一所公立大学，1862年设立，是南达科他州最初的公立大学。学生约1万人。

南达科他大学培养了不少著名人士，涵盖不同学科，尤以护理和教育为知名。 在台毕业校友以教育学院毕业生为主，主修涵盖高等教育、教育行政、成人教育、体育等教育相关学位博、硕士。

The University of South Dakota (or informally USD or the U) is a public coeducational research university located in the small town community of Vermillion, South Dakota. USD was established by the Dakota Territory legislature in 1862, 37 years before the establishment of the state of South Dakota (first classes held 1882 in the Clay County Courthouse), USD is the oldest public university in the state.