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单词 Tumourigenesis
释义

Tumourigenesis

中文百科

癌变 Carcinogenesis

（重定向自Tumourigenesis）
癌症是由一系列的基因突变造成的。每个突变对于细胞接下来的运作都可能会有所影响。
当正常细胞发生无法修复的损伤时，会进行细胞凋亡（图A），但癌细胞并不受到控制，反而持续进行生长复制（图B）。

癌变（英语：carcinogenesis）通常用来形容正常细胞转变成癌细胞的致癌过程，是细胞DNA受损突变后发生在细胞及基因级别上的、从而导致细胞不受机体控制恶性增殖的一系列改变，最终引起恶性肿瘤的形成。癌变是个复杂、受到多种因素控制的多阶段演变过程，它也是个可逆转的细胞转化过程。细胞内基因的突变和肿瘤的发生与遗传，环境等多种因素有关。

英语百科

Carcinogenesis 癌变

（重定向自Tumourigenesis）
Cancers are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat.
The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis
Longitudinally opened freshly resected colon segment showing a cancer and four polyps. Plus a schematic diagram indicating a likely field defect (a region of tissue that precedes and predisposes to the development of cancer) in this colon segment. The diagram indicates sub-clones and sub-sub-clones that were precursors to the tumors.
Tissue can be organized in a continuous spectrum from normal to cancer.

Carcinogenesis or oncogenesis or tumorigenesis is the actual formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by a progression of changes at the cellular, genetic, and epigenetic level that ultimately reprogram a cell to undergo uncontrolled cell division, thereby forming a malignant mass.
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更新时间：2025/6/20 3:34:46