" To screw up" means to make a mess.

“搞砸”就是弄得一团糟。

But how’s my Kindle gonna screw things up?

但为什么我的Kindle会毁掉这台飞机？

" To screw up" is to make a very big mistake.

To screw up 就是犯了一个非常大的错误。

No, no, no. No, I mean it's really gonna screw me up.

不 不 不 不 这会打乱我的计划的。

I just, um...I-I don't wanna do anything to screw it up.

我，呃......不想给你们添乱而已。

How was I supposed to know he was gonna screw up our investments that badly?

我怎么知道他让咱的投资打了水漂？

You don't want to screw up the one pair of eyes that you've got.

你可不想毁掉已有的一双眼睛。

If I have to go back in there, I'm just gonna screw it up.

如果我回去，我还是会搞砸。

Good time to screw up when he's reading the paper; bad time to screw up when he is laying bricks.

他看报纸的时候是正确的捣乱时机；他砌砖头的时候是错误的捣乱时机。

Don't forget to screw the paper up, otherwise the tree looks too flat and very uniform.

不要忘记拧纸了，否则树看起来太平整，非常统一。

What can I do? Look, I don't want to do anything to screw it up with Ursula.

我能怎么办？我不想让乌苏拉不开心。

" The longer X spends considering what to make, the less time he has to screw it up."

“某人花在考虑做什么上的时间越长，他把事情搞砸的时间就越少。”

What can I do? Look, I don't want to do anything to screw it up with Ursula.

能怎么办 我不想搞砸和乌苏拉这边的事。

Because I don't want to screw that up, and let's face it, Lynette. You know I would.

因为我不想再毁了这一切，勒奈特，你我都清楚，我肯定会的。

Eventually, you know, hopefully that other person's gonna screw up and then you're gonna be right there. Bam!

最后，希望那个人会搞砸，然后由你取代。砰！

Anyway this is probably my last shot with Penny and I don't want to screw it up. -Nobody wants that.

总之这是我和佩妮的最后机会了，我不想搞砸了。谁想搞砸啊。

To tell you the truth, I thought if anyone was going to screw things up for Howard, it'd be Sheldon.

老实说 就算有人会搞砸 霍华德的安全审核我也觉得应该是谢尔顿的错。

To screw up means to get something wrong.

To screw up 就是把事情搞砸了。

There's really two ways to screw this up.

真的有两种方法可以搞砸。

" To screw up" can also be related to your mental health.

“搞砸”也可能与您的心理健康有关。