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单词 Synaptotagmin
释义

Synaptotagmin

原声例句
经济学人-科技

The toxin molecules attach themselves to a protein called synaptotagmin, which is found on the surface membranes of nerve cells at their junctions with muscle cells.

这种毒素能结合到一种叫做synaptotagmin(SYT)的蛋白上,SYT则位于神经肌肉接头处神经细胞的细胞膜表面。

英语百科

Synaptotagmin 1

Molecular machinery driving exocytosis in neurotransmitter release: the core SNARE complex (formed by four α-helices contributed by synaptobrevin, syntaxin and SNAP-25) and the Ca2+ sensor synaptotagmin.[1]

Synaptotagmin 1 (or synaptotagmin) is a Ca sensor in the membrane of the pre-synaptic axon terminal, coded by gene SYT1 (previously SYT) at 12q21.2 (MIM:185605).

Synaptotagmins (SYTs) constitute a family of membrane-trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins.

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更新时间:2025/6/19 0:49:30