大都市统计区(United States Metropolitan Statistical Areas，简称MSA) 是在美国核心都市人口密度相对较高，和地区全体经济有密切关系的地理区域。这些地区并没有法律地位，由美国人口普查局和其他联邦政府机构出于统计目的使用。核心都市区域人口超过5万人的，可被定为大都市统计区。有些相邻的大都市统计区被合称为联合统计区(Combined Statistical Area，简称：CSA)。人口多于1万但少于5万的，则是小城市统计区(United States Micropolitan Statistical Areas，简称µSA) 。

In the United States, a metropolitan statistical area (MSA) is a geographical region with a relatively high population density at its core and close economic ties throughout the area. Such regions are neither legally incorporated as a city or town would be, nor are they legal administrative divisions like counties or separate entities such as states. As such, the precise definition of any given metropolitan area can vary with the source. A typical metropolitan area is centered on a single large city that wields substantial influence over the region (e.g., Chicago or Atlanta). However, some metropolitan areas contain more than one large city with no single municipality holding a substantially dominant position (e.g., Dallas–Fort Worth metroplex, Norfolk-Virginia Beach (Hampton Roads), Riverside–San Bernardino (Inland Empire) or Minneapolis–Saint Paul).