Sorbinil

Sorbinil is an aldose reductase inhibitor being investigated for treatment of diabetic complications including neuropathy and retinopathy. Aldose reductase is an enzyme present in lens and brain that gets rid of excess glucose by converting it to sorbitol. Sorbitol accumulation can lead to the development of cataracts in the lens and neuropathy in peripheral nerves. Sorbinil has been shown to inhibit aldose reductase in human brain and placenta and calf and rat lens. Sorbinil reduced sorbitol accummulation in rat lens and sciatic nerve of diabetic rats orally administered 0.25mg/kg sorbinil.

单词	Sorbinil
释义	Sorbinil 英语百科 Sorbinil Sorbinil is an aldose reductase inhibitor being investigated for treatment of diabetic complications including neuropathy and retinopathy. Aldose reductase is an enzyme present in lens and brain that gets rid of excess glucose by converting it to sorbitol. Sorbitol accumulation can lead to the development of cataracts in the lens and neuropathy in peripheral nerves. Sorbinil has been shown to inhibit aldose reductase in human brain and placenta and calf and rat lens. Sorbinil reduced sorbitol accummulation in rat lens and sciatic nerve of diabetic rats orally administered 0.25mg/kg sorbinil.
随便看	plain dry fish的意思 plain Dunstable的意思 plain的意思 plained的意思 plain edge的意思 plain elbow的意思 plain embossed design的意思 plain embroidery traycloth的意思 plain end的意思 plain ended pipe的意思 plain ended screw的意思 plain end joint的意思 plain end of pipe的意思 plain end pipe的意思 plain ends的意思 plain end steel pipe的意思 plain end tube的意思 plain end wheel drill的意思 Plain English的意思 Plain English Campaign的意思 plain equal cross的意思 plain equal side outet的意思 plain equal side outlet elbow的意思 plain equal tee的意思 plainer的意思