| 单词 | Serum response factor |
| 释义 |
Serum response factor
英语例句库
Analysis of the expression of transcription factors required for cardiogenesis revealed downregulation of key cardiac transcription factors such as the serum response factor, Gata4, and Nkx2–5. 分析这些心脏基因所必须的转录因子表达，显示出关键的几种心脏转录因子失调，如血浆反应因子，Gata4和Nkx2–5。
英语百科
Serum response factor    Serum response factor, also known as SRF, is a transcription factor. Serum response factor is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). |
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