RNA helicase

A helicase in general is defined as “any of various enzymes that catalyze the unwinding and separation of double-stranded DNA or RNA during its replication”. A helicase is more specifically considered a motor enzyme which receives its energy from nucleoside triphosphate hydrolysis to unwind double stranded nucleic acids. In our case we are considering specifically RNA Helicase which is involved holistically in the metabolism of RNA which is found in all facets of life on earth. RNA helicase (EC3.6.4.13, CSFV NS3 helicase, DBP2, DbpA, DDX17, DDX25, DDX3, DDX3X, DDX3Y, DDX4, DDX5, DEAD-box protein DED1, DEAD-box RNA helicase, DEAD-box protein 2, DEAH-box RNA helicase, DED1, Dex(H/D) RNA helicase, EhDEAD1, EhDEAD1 RNA helicase, eIF4A helicase, KOKV helicase, Mtr4p, nonstructural protein 3 helicase, NPH-II, RHA, RNA helicase A, RNA helicase DDX3, RNA helicase Hera, RNA-dependent ATPase, TGBp1 NTPase/helicase domain, VRH1, GRTH/DDX25) is an enzyme with systematic name ATP phosphohydrolase (RNA helix unwinding). This enzyme catalyses the following chemical reaction