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单词 Pyridinium chlorochromate
释义

Pyridinium chlorochromate

中文百科

氯铬酸吡啶盐

氯铬酸吡啶盐,分子式C5H4N·HCrO3Cl,简称PCC,即Pyridinium chlorochromate的缩写。一种温和的氧化剂,橙黄色晶体。用来把醇有限度地氧化为醛,使用PCC的缺点为反应时间太过冗长和PCC具有毒性。

由E.J.Corey发明。试剂本身呈弱酸性,所以常跟缓冲剂比如乙酸钠配合使用。

英语百科

Pyridinium chlorochromate 氯铬酸吡啶盐

Pyridinium chlorochromate (PCC) is a red–orange salt with the formula C5H5NH[CrO3Cl]. It is a reagent in organic synthesis used primarily for the oxidation of alcohols to form carbonyls. A variety of related compounds are known with similar reactivity. Although no longer widely used, PCC offered the advantage of the selective oxidation of alcohols to aldehydes, whereas many other reagents were less selective. Disadvantages to using PCC are the tedious reaction workup and its toxicity. The chemical was first synthesized and used by E.J. Corey and J. William Suggs.

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更新时间:2025/6/19 17:50:23