Premature ovarian failure
(重定向自Primary ovarian failure)
Premature ovarian failure (POF), also known as premature ovarian insufficiency (POI), or primary ovarian insufficiency is the loss of function of the ovaries before age 40. A commonly cited triad for the diagnosis is amenorrhea, hypergonadotropism, and hypoestrogenism. If it has a genetic cause, it may be called gonadal dysgenesis