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单词 autoreceptor
释义

autoreceptor

英汉-汉英词典
自身受体
词组 | 习惯用语
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  • interception n. 拦截,截住;侦听,窃听;截断,截取
  • receptor n. 受体;接受器;感觉器官
  • interceptor n. 拦截机
  • preceptor n. 教师;训导者;圣殿骑士地方分团团长
autoreceptor n. 自受体

网络短语:
Autoreceptors Autoreceptor 自受体
英语百科

Autoreceptor

This diagram shows pre-synaptic neuron (left) releasing a neurotransmitter, noradrenaline (norepinephrine), into the synaptic cleft. The transmitter acts on the receptors of the post-synaptic neuron (right), but also on autoreceptors of the pre-synaptic neuron. Activation of these autoreceptors typically inhibits further release of the neurotransmitter.Amphetamine, trace amines, and dopamine can activate TAAR1 in dopamine neurons, but only dopamine activates D2sh.  These receptors have opposite effects on protein kinase signaling. This results in opposite effects on DAT phosporylation, and consequently, on reuptake as well.
A pharmacodynamic model of amphetamine and TAAR1

An autoreceptor is a type of receptor located in the membranes of presynaptic nerve cells. It serves as part of a negative feedback loop in signal transduction. It is only sensitive to the neurotransmitters or hormones released by the neuron on which the autoreceptor sits. Similarly, a heteroreceptor is sensitive to neurotransmitters and hormones that are not released by the cell on which it sits. A given receptor can act as either an autoreceptor or a heteroreceptor, depending upon the type of transmitter released by the cell on which it is embedded.

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更新时间:2025/6/16 22:35:13