皮耶克赛迈基（芬兰语：Pieksämäki）是芬兰东芬兰省的一个镇。

Pieksämäki is a town and municipality of Finland.

It is located in the province of Eastern Finland and is part of the Southern Savonia region.The town has a population of 18,999 (30 June 2015) and covers an area of 1,836.39 square kilometres (709.03 sq mi) of which 266.76 km (103.00 sq mi) is water. The population density is 12.1 inhabitants per square kilometre (31/sq mi).. Neighbour municipalities are Hankasalmi, Joroinen, Juva, Kangasniemi, Leppävirta, Mikkeli, Rautalampi and Suonenjoki.