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单词 Nucleotide analogue
释义

Nucleotide analogue

原声例句
医学之光:人类与疾病的斗争

Treatment with intravenous remdesivir (a novel nucleotide analogue prodrug in development) was initiated on the evening of day 7, and no adverse events were observed in association with the infusion.

第 7 天晚上开始静脉注射瑞德西韦(一种正在开发的新型核苷酸类似物前药)治疗, 未观察到与输注相关的不良事件。

中文百科

逆转录酶抑制剂 Reverse-transcriptase inhibitor

(重定向自Nucleotide analogue)

核苷类逆转录酶抑制剂英语:Nucleoside Reverse Transcriptase Inhibitors,简称NRTIs),是合成HIV的DNA逆转录酶底物脱氧核苷酸的类似物,在体内转化成活性的三磷酸核苷衍生物,与天然的三磷酸脱氧核苷竞争性与HIV逆转录酶(RT)结合,抑制RT的作用,阻碍前病毒的合成。

已上市的NRTIs药物有:齐多夫定、去羟肌苷、扎西他滨、司坦夫定、拉米夫定、阿巴卡韦等。

英语百科

Reverse-transcriptase inhibitor 逆转录酶抑制剂

(重定向自Nucleotide analogue)

Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses.

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更新时间:2025/6/23 5:12:03