Because it is hard to industrify the production of the targeting-medicant by this method ,we decide to research the expression of apoAI gene in methytrophic yeast Pichia pastoris system . 因此，我们决定运用毕赤氏酵母表达系统进行ApoAI的表达研究，将获得的rApoAI作为一个新的载体，为制备新型的靶向药物创造条件。