Ligand-gated ion channel

Illustration depicting Acetylcholine (ACh) ligand gated channel.

Nicotinic acetylcholine receptor in closed state with predicted membrane boundaries shown, PDB 2BG9

The AMPA receptor bound to a glutamate antagonist showing the amino terminal, ligand binding, and transmembrane domain, PDB 3KG2

Ligand-gated ion channels (LGICs) are a group of transmembrane ion channel proteins which open to allow ions such as Na, K, Ca, or Cl to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.

单词	LGIC
释义	LGIC 英语百科 Ligand-gated ion channel Ligand-gated ion channels (LGICs) are a group of transmembrane ion channel proteins which open to allow ions such as Na, K, Ca, or Cl to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.
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