Lambesc is a commune in the Bouches-du-Rhône department in the Provence-Alpes-Côte d'Azur region in southern France.

Lambesc is located in the heart of Provence at the foot of the Côtes mountain range, near the Alpilles. The village has a strong historical and cultural heritage, being home to the Church of Our Lady of the Assumption, the eleventh-century Romanesque chapel of St. Anne's Goiron, and Manivert, a local art and archaeological museum. The special character of the village and its beautiful environs (including the Luberon) attracts many tourists.