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单词 Hypergastrinemia
释义

Hypergastrinemia

英语百科

Gastrin

G cell is visible near bottom left, and gastrin is labeled as the two black arrows leading from it. Note: this diagram does not illustrate gastrin's stimulatory effect on ECL cells.

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.

Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K/H ATPase pumps into the apical membrane of parietal cells (which in turn increases H release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.

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更新时间:2025/6/17 9:37:35