Factor Xa, with Factor Va as a cofactor, turns factor II (also called prothrombin) into factor IIa or thrombin.
活性因子Xa和作为辅因子的因子Va将因子II（凝血酶原）转变为因子IIa（凝血酶）。
Factor IIa
原声例句
Osmosis-血液肿瘤
英语百科
Thrombin
![Anchoring of bovine prothrombin to the membrane through its Gla domain.[8]](/uploads/202501/12/1nl2_opm0347.png)
Thrombin (EC3.4.21.5, fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease that, in humans, is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.
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