外来偶蹄类脑病（英语：Exotic ungulate encephalopathy，缩写为EUE），传染性海绵状脑病的一种，由普利昂蛋白质引起的脑病变，主要侵袭在动物园中被人类饲养的动物。在1990年代开始，在英国动物园中的多个物种就被发现感染了这个疾病，包括扭角林羚、安氏林羚、南非剑羚、伊兰羚羊、阿拉伯大羚羊、弯角剑羚、Ankole-Watusi牛、与美洲野牛。最近一次病例出现在1998年。研究指出，这个疾病的传染途径，可能是经由动物饲料中添加的肉骨粉。

Exotic ungulate encephalopathy is a transmissible spongiform encephalopathy (TSE), or prion disease, identified in infected organs of zoo animals. This subgroup of the TSEs in captive animals was identified in zoo animals in Great Britain including species of greater kudu, nyala, gemsbok, the common eland, Arabian and Scimitar Oryx, an Ankole-Watusi cow, and an American bison. Studies indicate that transmission likely occurred via the consumption of feed supplemented with meat and bone meal, although some animals died after the British ban on ground offal in animal feed. All animals died during the 1990s, with the last death occurring in 1998.