埃庇卡摩斯（希腊语：Επίχαρμος，拉丁化：Epicharmus；前540年－前450年），希腊喜剧剧作家、哲学家，对西西里、多里安的戏剧影响甚大。现代人对埃庇卡摩斯的认识主要源于《苏达辞书》和阿特纳奥斯、第欧根尼·拉尔修的作品。

Epicharmus of Kos or Epicharmus Comicus or Epicharmus Comicus Syracusanus (Greek: Ἐπίχαρμος), is thought to have lived within the ninety-year period between c. 540 and c. 450 BC. He was a Greek dramatist and philosopher often credited with being one of the first comic writers, having originated the Doric or Sicilian comedic form. Aristotle (Poetics 5.1449b5) writes that he and Phormis invented comic plots (μῦθος, muthos). Most of the information we have about Epicharmus comes from the writings of Athenaeus, Suda and Diogenes Laertius, but fragments and comments come up in a host of other ancient authors as well. There have also been some papyrus finds of longer sections of text, but these are often so full of holes that it is difficult to make sense of them. Plato mentions Epicharmus in his dialogue Gorgias and in Theaetetus. In the latter, Socrates refers to Epicharmus as "the prince of Comedy", Homer as "the prince of Tragedy", and both as "great masters of either kind of poetry". More references by ancient authors can be found discussed in Pickard-Cambridge's Dithyramb, Tragedy, Comedy and they are collected in Greek in Kassel and Austin's new edition of the fragments in Poetae Comici Graeci (2001).