Like what are some troubles that you had that really drove you nuts?

比如你们遇到了哪些让你们抓狂的麻烦？

NINA TOTENBERG: But do you...what's it like to lose a lot? Does that drive you nuts?

但是你… … 失去很多是什么感觉？这让你抓狂吗？

You could say something drives you nuts.

你可以说有些事情让你发疯。

She drove you nuts before too, remember?

以前她也快把你逼疯了，记得吗？

She's staying with you, and she's driving you nuts.

她住到你那儿去了 把你逼疯了。