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单词 DOPAC
释义

DOPAC

原声例句
医学英语视频

However, lets not forget that dopamine is also susceptible to breakdown by COMT as well as MAO-B, which convert dopamine to 3-methoxytyramine (3-MT) and 3,4dihydroxyphenylacetic acid (DOPAC) respectively.

然而,我们不要忘记多巴胺也容易被COMT分解如MAO-B,可将多巴胺转化为3-甲氧基酪胺(3-MT)和3,4-二羟基苯乙酸(DOPAC)分别。

英语百科

3,4-Dihydroxyphenylacetic acid

(重定向自DOPAC)
Biodegradation of dopamine

3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine.

Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).

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更新时间:2025/6/17 6:50:10