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单词 Distal renal tubular acidosis
释义

Distal renal tubular acidosis

中文百科

远程肾小管酸中毒

佝偻病患者的X光造影(Radiography),显示出有远程及近端的RTA并发症.
Diagram depicting an alpha intercalated cell with the apical proton pump and basolateral band 3 (kAE1)

远程肾小管性酸中毒(Distal renal tubular acidosisdRTA、或"1型肾小管酸中毒"(RTA 1))是RTA的传统形式,为RTA第一个描述的病症。远程RTA的特征在于远程肾单位的集合管系统(Collecting duct system)的"α-闰细胞"(alpha intercalated cells)酸分泌的失败。这种酸分泌的失败可能是由于多种原因,且会导致没有能力来酸化尿液使其pH值小于<5.3>。

英语百科

Distal renal tubular acidosis 远端肾小管酸中毒

Radiograph of a rickets sufferer, a complication of both distal and proximal RTA.
Diagram depicting an alpha intercalated cell with the apical proton pump and basolateral band 3 (kAE1)

Distal renal tubular acidosis (dRTA) or Type 1 renal tubular acidosis (RTA) is the classical form of RTA, being the first described. Distal RTA is characterized by a failure of acid secretion by the alpha intercalated cells of the cortical collecting duct of the distal nephron. This failure of acid secretion may be due to a number of causes, and it leads to an inability to acidify the urine to a pH of less than 5.3.

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更新时间:2025/6/23 8:16:21