Aldolase A

原声例句

经济学人（汇总）

Dr List worked on an enzyme called aldolase A. This catalyses what is known as the aldol reaction, an important way of forging molecular bonds between carbon atoms.

利斯特博士研究了一种名为醛缩酶A的酶，这种酶催化所谓的醛缩反应，这是一种在碳原子之间形成分子键的重要方式。

经济学人（汇总）

Aldolase A is made of 350 amino acids, the building blocks of proteins, but the bit that does the work consists of only three of these: lysine, glutamic acid and tyrosine. The rest of the enzyme is packaging.

醛缩酶A由350种氨基酸组成，这些氨基酸是蛋白质的组成成分，但起作用的部分只有三个：赖氨酸、谷氨酸和酪氨酸。剩下的酶是包装的。

中文百科

醛缩酶A

醛缩酶A（英语：Aldolase A）是一种酶，可使果糖-1,6-双磷酸断裂转变成为甘油醛-3-磷酸和二羟丙酮磷酸。是糖解作用里的一部分。

β-D-果糖1,6-二磷酸	果糖二磷酸醛缩酶	D-甘油醛3-磷酸		二羟丙酮磷酸
			+




	果糖二磷酸醛缩酶

位于KEGG途径数据库化合物 C05378 位于KEGG途径数据库的酶4.1.2.13 位于KEGG途径数据库化合物 C00111 位于KEGG途径数据库化合物 C00118

英语百科

Aldolase A 醛缩酶A

The reaction mechanism of aldolase.The enzyme's reactive site amino acid's side-chains are shown in blue.Abbreviations: DHAP - dihydroxyacetone phosphate; Fru1,6bP - Fructose-1,6-bisphosphate; GAD - glyceraldehyde 3-phosphate;

Aldolase A (ALDOA, or ALDA), also known as fructose-bisphosphate aldolase, is an enzyme that in humans is encoded by the ALDOA gene on chromosome 16.

The protein encoded by this gene is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]

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