Denosumab

Denosumab (trade names include Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.

The most common side effects are joint and muscle pain in the arms or legs. Denosumab is contraindicated in people with low blood calcium levels. Denosumab is a RANKL inhibitor, which works by preventing the development of osteoclasts which are cells that break down bone. It was developed by the biotechnology company Amgen.

单词	Denosumab
释义	Denosumab 原声例句 Osmosis-肌骨 Finally, medications like denosumab, which is a monoclonal antibody that inhibits osteoclasts, and raloxifene, which is a selective estrogen receptor modulator, can be used for postmenopausal osteoporosis. 最后，地诺单抗等药物作为单克隆抗体可抑制破骨细胞；雷洛昔芬，一种有选择性的雌激素受体调节器，可以被用于绝经后骨质疏松。英语百科 Denosumab Denosumab (trade names include Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. The most common side effects are joint and muscle pain in the arms or legs. Denosumab is contraindicated in people with low blood calcium levels. Denosumab is a RANKL inhibitor, which works by preventing the development of osteoclasts which are cells that break down bone. It was developed by the biotechnology company Amgen.
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