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单词 Decapentaplegic
释义

Decapentaplegic

中文百科

Decapentaplegic

Decapententaplegic缩写为Dpp.是生物皮肤的生长因子。它在皮肤表面影响着生物背部的颜色。

dpp基因从复制、转录到dpp蛋白的翻译过程如图所示。

如果DNA上的dpp gene发生突变,原来的G-C碱基对突变为A-T碱基对。将会导致最后翻录出来的蛋白无法连接起来,从而引起皮肤的肤色发生改变。

英语百科

Decapentaplegic

Decapentaplegic (Dpp) is a key morphogen involved in the development of the fruit fly Drosophila melanogaster. It is known to be necessary for the correct patterning of the fifteen imaginal discs, which are tissues that will become limbs and other organs and structures in the adult fly. It has also been suggested that Dpp plays a role in regulating the growth and size of tissues. Flies with mutations in decapentaplegic fail to form these structures correctly, hence the name (decapenta-, fifteen, -plegic, paralysis). Dpp is the Drosophila homolog of the vertebrate bone morphogenetic proteins (BMPs), which are members of the TGF-β superfamily, a class of proteins that are often associated with their own specific signaling pathway. Studies of Dpp in Drosophila have led to greater understanding of the function and importance of their homologs in vertebrates like humans.

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更新时间:2025/6/21 5:13:35