Cystathionine gamma-lyase
(重定向自Cystathionase)



![Inhibited cystathionase active site.[2] The inhibitor and Tyr114 are in light blue, PLP in purple, and Lys121 in yellow.](/uploads/202501/07/Cystathionase_inhibited_zoomed5310.png)
Cystathionine gamma-lyase (CTH or CSE) (also cystathionase) is an enzyme which breaks down cystathionine into cysteine, α-ketobutyrate, and ammonia. Pyridoxal phosphate is a prosthetic group of this enzyme.
Cystathionine gamma-lyase also catalyses the following elimination reactions: