东部菱背响尾蛇（学名Crotalus adamanteus）为北美洲最大最重的毒蛇，最常可达7英呎。东部菱背响尾蛇的名称来自于背上明显的菱形背斑，能使牠们融入落叶林的地层。东部菱背响尾蛇有时会游泳穿梭于外海的各个岛屿，最远能游离岸边20000码的岛屿。游客有时会在登山步道上遇见牠们，有时会不经意的踩到使牠们来不及摇动响环警告而激起牠们的自卫本能，使东部菱背响尾蛇在该地声名狼藉。

Common names: eastern diamondback rattlesnake, eastern diamondback, more

Crotalus adamanteus is a pit viper species found in the southeastern United States. It is the heaviest though not the longest venomous snake in the Americas and the largest rattlesnake. No subspecies are currently recognized.