颅骨变形（英语：cranial deformation）是人体改造的一种，人为地使人的头盖骨变形。

新生儿至婴儿期间，头骨尚未定型，略显不规则。此后经过一系列自然成长过程逐渐变得规则，在囟门闭合之后定型。有些民族的文化中，会以自己的审美观点对颅骨形状进行改造。

在古代，颅骨变形改造非常普遍。古代的匈人会对新生儿颅骨进行改造。在欧洲，以克里米亚为中心，在英国、瑞士、德国、奥地利、匈牙利等国的前基督教时代古墓中，均有发现颅骨改造过的尸体。而在美洲，古代的玛雅人和印加人都普遍存在对颅骨的变形改造，他们用木板将新生儿的头夹起来，或者用布带缠绕起来，使头形变长。

Artificial cranial deformation, head flattening, or head binding is a form of body alteration in which the skull of a human being is deformed intentionally. It is done by distorting the normal growth of a child's skull by applying force. Flat shapes, elongated ones (produced by binding between two pieces of wood), rounded ones (binding in cloth), and conical ones are among those chosen. Typically, it is carried out on an infant, as the skull is most pliable at this time. In a typical case, headbinding begins approximately a month after birth and continues for about six months.