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单词 CpG islands
释义

CpG islands

原声例句
Osmosis-消化

Within the DNA of the cells in these polyps, there are specific stretches of nucleotides that are called CpG islands.

息肉细胞的DNA中有一些特定的核苷酸序列被称为CpG岛。

Osmosis-消化

CpG islands are found in most promoter regions of genes which are the DNA sequences responsible for the initiation of gene transcription.

CpG岛位于绝大部分启动子区域，是一组负责转录起始的DNA序列。

中文百科

CpG位点 CpG site

（重定向自CpG islands）
How methylation of CpG sites followed by spontaneous deamination leads to a lack of CpG sites in methylated DNA. As a result residual CpG islands are created in areas where methylation is rare, and CpG sites stick (or where C to T mutation is highly detrimental).
An image showing a hypothetical evolutionary mechanism behind CpG island formation.
CpG,

CpG位点（英语：CpG sites，或称为CG位点）是指DNA的某个区域，其上的碱基串行以胞嘧啶接着鸟嘌呤出现。“CpG”是“—C—磷酸—G—”的缩写 ，指磷酸二酯键连接了胞嘧啶和鸟嘌呤，其中C位于5'端而G位于3'端。

在CpG位点中的胞嘧啶可以被甲基化为5-甲基胞嘧啶。在哺乳动物中，基因内CpG位点的甲基化会改变此基因的表达，对这一表达调控的研究是表观遗传学的重要组成部分。涉及添加甲基基团的酶称为DNA甲基转移酶。

英语百科

CpG site CpG位点

（重定向自CpG islands）
CpG,
How methylation of CpG sites followed by spontaneous deamination leads to a lack of CpG sites in methylated DNA. As a result, residual CpG islands are created in areas where methylation is rare, and CpG sites stick (or where C to T mutation is highly detrimental).
An image showing a hypothetical evolutionary mechanism behind CpG island formation.

The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction. CpG is shorthand for 5'—C—phosphate—G—3' , that is, cytosine and guanine separated by only one phosphate; phosphate links any two nucleosides together in DNA. The CpG notation is used to distinguish this single-stranded linear sequence from the CG base-pairing of cytosine and guanine for double-stranded sequences. The CpG notation is therefore to be interpreted as the cytosine being 5 prime to the guanine base. CpG should not be confused with GpC, the latter meaning that a guanine is followed by a cytosine in the 5' → 3' direction of a single-stranded sequence.
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更新时间：2025/6/18 14:10:52