In the central nervous system, nicotinic receptors are on pre-synaptic axon terminals of neurons, and when nicotine binds to them, it triggers the release of neurotransmitters like dopamine, acetylcholine, and glutamate, which is why it's considered an acetylcholine agonist.

在中枢神经系统中，烟碱受体分布于突触前神经元的轴突末端，当尼古丁与受体结合后，会触发多巴胺、乙酰胆碱、谷氨酸盐等神经递质的释放，因此尼古丁被认为是一种乙酰胆碱受体兴奋剂。