Coarctation of the aorta

Schematic drawing of alternative locations of a coarctation of the aorta, relative to the ductus arteriosus. A: Ductal coarctation, B: Preductal coarctation, C: Postductal coarctation. 1: Aorta ascendens, 2: Arteria pulmonalis, 3: Ductus arteriosus, 4: Aorta descendens, 5: Truncus brachiocephalicus, 6: Arteria carotis communis sinistra, 7: Arteria subclavia sinistra

Illustration depicting Coarctation of the Aorta.

Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word “coarctation” means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with coarctations. Other heart defects may also occur when coarctation is present, typically occurring on the left side of the heart. When a patient has a coarctation, the left ventricle has to work harder. Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in lack of blood to the lower half of the body. Physiologically its complete form is manifested as interrupted aortic arch.

单词	Coarctation of the aorta
释义	Coarctation of the aorta 原声例句 Osmosis-遗传 Coarctation of the aorta and a bicuspid aortic valve can cause lower extremity cyanosis, meaning a bluish or purplish discoloration of the lower limbs, and can result in congestive heart failure. 主动脉缩窄和二叶式主动脉瓣畸形会导致下肢紫绀，意味着下肢呈青紫色，并可导致充血性心力衰竭。 Osmosis-遗传 There are also plenty of other unidentified genes on the X chromosome, so individuals with Turner syndrome are predisposed to cardiovascular defects like preductal coarctation of the aorta and bicuspid aortic valve. X染色体上还有很多其它未被识别的基因，所以特纳综合征患者容易出现心血管缺陷疾病，如导管前型主动脉缩窄、二叶式主动脉瓣畸形。英语百科 Coarctation of the aorta Coarctation of the aorta (CoA or CoAo), also called aortic narrowing, is a congenital condition whereby the aorta is narrow, usually in the area where the ductus arteriosus (ligamentum arteriosum after regression) inserts. The word “coarctation” means narrowing. Coarctations are most common in the aortic arch. The arch may be small in babies with coarctations. Other heart defects may also occur when coarctation is present, typically occurring on the left side of the heart. When a patient has a coarctation, the left ventricle has to work harder. Since the aorta is narrowed, the left ventricle must generate a much higher pressure than normal in order to force enough blood through the aorta to deliver blood to the lower part of the body. If the narrowing is severe enough, the left ventricle may not be strong enough to push blood through the coarctation, thus resulting in lack of blood to the lower half of the body. Physiologically its complete form is manifested as interrupted aortic arch.
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