Factor XIII

Factor XIII or fibrin stabilizing factor is an enzyme (EC2.3.2.13) of the blood coagulation system that crosslinks fibrin. Deficiency of this factor (FXIIID) affects clot stability. FXIIID, while generally rare, Iran has the highest global incidence of disorder with 473 cases; the city of Khash has the highest incidence in Iran, as it is in Sistan and Balochistan provinces with high rate of consanguineous marriage.