Those diagnosed with heart disease had significantly greater baseline clotting factors.

那些被确诊有心脏病的患者，动脉中出现凝血的可能性更高。

This active protein then proteolytically cleaves and activates the next clotting factor, and so on.

然后这一活化的凝血因子激活另一个未活化的凝血因子，以此类推。

Here's a study showing that Cardiovascular disease clearly increases with an increase in the clotting factor fibrinogen.

这项研究显示，体内纤维蛋白原（一种导致凝血的因素）越多，罹患心血管疾病的风险就越高。

Treatment for hemophilia A and B are done with injections of the missing or nonfunctional clotting factor.

治疗血友病A和B的方法通常是注射那些缺失或失活的凝血因子。

" We've developed bandages with clotting factors on them to put on the wounds, which were big advances" .

" 我们已经开发了上面带有凝血因子的绷带，可以放在伤口上，这是很大的进步。"

Another cause is autoimmunity against a clotting factor, and finally, there is disseminated intravascular coagulation which consumes coagulation factors.

另一个病因是自身免疫因素对抗凝血因子，最后还有弥散性血管内凝血，会消耗凝血因子。

So the activation of the cascade is carefully controlled by anticoagulation proteins that target and inactivate key clotting factors.

因此这一级联反应的活化同时需要抗凝因子的精密调控，这些抗凝因子主要是作用于关键的凝血因子并且可以使它们失活。

DIC, though, is also called a consumption coagulopathy, because all this clotting consumes platelets and clotting factors.

尽管如此，DIC也被称为消耗性凝血病，因为所有的凝血过程都消耗血小板和凝血因子。

The massive formation of clots throughout the body depletes the supply of platelets and clotting factors.

全身血凝块的大量形成耗竭了血小板和凝血因子。

The second factor is a state of hypercoagulation, where altered amounts of clotting factors increase primary or secondary hemostasis.

第二个因素是高凝状态，高凝状态下凝血因子数量增多，会增强初期或二期凝血。